Transborder Fix line transect are used to assess amount, composition, and spatial distribution of floating macro litter, bigger than 20 cm, along fixed trans-border transects in the Mediterranean basin. The transects, monitored all year round, cross the south east partof Ligurian Sea, Sardinian Balearic basin, Bonifacio Strait, Central Tyrrhenian Sea, Sicilian Sardinian Channels, Adriatic Sea , and Ionian Sea. The surveyed area en-compasses a large portion of the Mediterranean Sea and falls withinthree MSFD marine subregions: the Western Mediterranean Sea, theAdriatic Sea, the Ionian and Central Mediterranean Sea.